Metabolic Factors Affecting Monoamine Oxidase Activity

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Demographic, biologic, and other variables affecting monoamine oxidase activity.

Monoamine oxidase (MAO) activity has been shown to be influenced by a variety of demographic, biologic, and other variables. Human platelet, plasma, and brain enzyme activities correlate with age and are higher in women. Brain catecholamines tend to decrease with age. The acute effects of ethanol on platelet MAO do not appear to be significant, but chronic ethanol ingestion could influence enzy...

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Platelet monoamine oxidase activity and headache.

Mean platelet monoamine oxidase activity was reduced compared with control values in groups of headache-free male (but not female) patients suffering from classical migraine and from tension headache. Mean activity in male cluster patients, headache free, both during acute and quiescent phases of their illness, was also notably reduced. Retesting some migraine subjects after up to four years, s...

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Platelet monoamine oxidase activity in Huntington's chorea.

The possibility that genetically determined abnormalities in the monoamine oxidase of certain central nervous system aminergic neurones may play a part in the pathology of Huntington's chorea was investigated using human platelet monoamine oxidase. Significantly elevated monoamine oxidase activity was found in male patients compared to control subjects suggesting this may be a screening test fo...

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Platelet monoamine oxidase activity in megaloblastic anaemia.

Platelet monoamine oxidase activity has been measured in 17 patients with megaloblastic anaemia due to either vitamin B12 or folate deficiency, and in 20 healthy subjects. There was a highly significant increase in patients compared with controls. In two patients, platelet activity decreased following successful treatment. A significant correlation between platelet activity and the severity of ...

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Platelet monoamine oxidase activity in diabetics.

Plateiet monoamine ox!dase (MAO) activity was determined, using benzylainine as substract. Results are expressed as nM benzaidehyde/nig protein hour, at 37. A total of 79 diabetics (40 M and 39 F) ranging in age from 3 to 70 years was stud,ed. A normal control group inciuded 39 persons (17 M and 22 F) ranging in age from 16 to 60 years. Piatelet MAO activity shows a slight variation in relation...

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ژورنال

عنوان ژورنال: Schizophrenia Bulletin

سال: 1980

ISSN: 0586-7614,1745-1701

DOI: 10.1093/schbul/6.2.308